Registered Nurse vs Nurse Practitioner salary in South Carolina
In South Carolina, nurse practitioners earn more — an estimated $123,290 a year versus $82,360 for registered nurses, a gap of about $40,930 (roughly 50% more). Both are estimates based on national pay for each role adjusted for South Carolina.
Registered Nurse — South Carolina
Verified public wage dataMedian annual pay
$82,360
-16% vs nationalHourly
$39.60/hr
- Typical range
- $77,320–$97,230
- What most nurses earn
- High end
- $106,520
- Top earners
- Entry level
- $66,860
- Newer nurses
Nurse Practitioner — South Carolina
Verified public wage dataMedian annual pay
$123,290
-7% vs nationalHourly
$59.27/hr
- Typical range
- $107,930–$132,220
- What most nurses earn
- High end
- $160,170
- Top earners
- Entry level
- $97,080
- Newer nurses
Why the gap in South Carolina
Nurse Practitioners — advanced practice nurses who diagnose and prescribe — earn well above staff RNs. The South Carolina figures apply the same local pay adjustment to both roles, so the gap here mirrors the national picture, shifted for South Carolina's cost of labor. Actual pay varies with experience, specialty, shift, and employer — compare the national Registered Nurse vs Nurse Practitioner comparison or personalize the calculator.
Registered Nurse vs Nurse Practitioner in South Carolina — FAQ
- Do registered nurses or nurse practitioners earn more in South Carolina?
- In South Carolina, nurse practitioners earn more — $123,290 a year versus $82,360 for registered nurses, a gap of about $40,930 (roughly 50% more). Both are median wages reported for South Carolina in official public wage data.
- How much is the registered nurse vs nurse practitioner pay gap in South Carolina?
- The reported gap in South Carolina is about $40,930 a year, or roughly 50% more for nurse practitioners. Your actual pay depends on experience, specialty, shift, and employer — use the calculator to compare both for your situation.
- Are these South Carolina figures exact?
- They're the median wages actually reported for South Carolina — meaning half of nurses in the role earn more and half earn less. A median is a real measured midpoint, not a prediction of your offer: your pay moves with experience, specialty, shift, overtime, and employer.
- Why are some figures verified and others estimates?
- National pay for the main nursing roles — registered nurses, LPNs/LVNs, nurse practitioners, CRNAs, nurse midwives, and nursing assistants — comes from verified public wage data. State, city, and specialty figures that aren't reported on their own start from that national pay and are labeled "Estimated" or "Specialty estimate." We never show an estimate as a verified figure.
Source & confidence— A verified figure from official U.S. public wage data.
BLS OEWS (May 2025, state)
South Carolina figures are published directly by the U.S. Bureau of Labor Statistics for South Carolina (May 2025). They are not estimated or adjusted.
Source year 2025. Last reviewed July 17, 2026. Full methodology
Estimated figures for South Carolina. Last reviewed July 17, 2026.