How much is the registered nurse vs nurse practitioner pay gap in Missouri?

The reported gap in Missouri is about $48,150 a year, or roughly 59% more for nurse practitioners. Your actual pay depends on experience, specialty, shift, and employer — use the calculator to compare both for your situation.

Are these Missouri figures exact?

They're the median wages actually reported for Missouri — meaning half of nurses in the role earn more and half earn less. A median is a real measured midpoint, not a prediction of your offer: your pay moves with experience, specialty, shift, overtime, and employer.

Why are some figures verified and others estimates?

National pay for the main nursing roles — registered nurses, LPNs/LVNs, nurse practitioners, CRNAs, nurse midwives, and nursing assistants — comes from verified public wage data. State, city, and specialty figures that aren't reported on their own start from that national pay and are labeled "Estimated" or "Specialty estimate." We never show an estimate as a verified figure.

Missouri · MO

Registered Nurse vs Nurse Practitioner salary in Missouri

In Missouri, nurse practitioners earn more — an estimated $129,930 a year versus $81,780 for registered nurses, a gap of about $48,150 (roughly 59% more). Both are estimates based on national pay for each role adjusted for Missouri.

Registered Nurse — Missouri

Verified public wage data

Median annual pay

$81,780

-16% vs national

Hourly

$39.32/hr

Median $81,780

$63,230Middle 50%: $76,050–$98,560$104,390

Typical range: $76,050–$98,560; What most nurses earn
High end: $104,390; Top earners
Entry level: $63,230; Newer nurses

Nurse Practitioner — Missouri

Verified public wage data

Median annual pay

$129,930

Near national

Hourly

$62.47/hr

Median $129,930

$100,650Middle 50%: $119,910–$144,640$162,060

Typical range: $119,910–$144,640; What most nurses earn
High end: $162,060; Top earners
Entry level: $100,650; Newer nurses

Why the gap in Missouri

Nurse Practitioners — advanced practice nurses who diagnose and prescribe — earn well above staff RNs. The Missouri figures apply the same local pay adjustment to both roles, so the gap here mirrors the national picture, shifted for Missouri's cost of labor. Actual pay varies with experience, specialty, shift, and employer — compare the national Registered Nurse vs Nurse Practitioner comparison or personalize the calculator.

Registered Nurse vs Nurse Practitioner in Missouri — FAQ

Do registered nurses or nurse practitioners earn more in Missouri?: In Missouri, nurse practitioners earn more — $129,930 a year versus $81,780 for registered nurses, a gap of about $48,150 (roughly 59% more). Both are median wages reported for Missouri in official public wage data.
How much is the registered nurse vs nurse practitioner pay gap in Missouri?: The reported gap in Missouri is about $48,150 a year, or roughly 59% more for nurse practitioners. Your actual pay depends on experience, specialty, shift, and employer — use the calculator to compare both for your situation.
Are these Missouri figures exact?: They're the median wages actually reported for Missouri — meaning half of nurses in the role earn more and half earn less. A median is a real measured midpoint, not a prediction of your offer: your pay moves with experience, specialty, shift, overtime, and employer.
Why are some figures verified and others estimates?: National pay for the main nursing roles — registered nurses, LPNs/LVNs, nurse practitioners, CRNAs, nurse midwives, and nursing assistants — comes from verified public wage data. State, city, and specialty figures that aren't reported on their own start from that national pay and are labeled "Estimated" or "Specialty estimate." We never show an estimate as a verified figure.

Source & confidence— A verified figure from official U.S. public wage data.

BLS OEWS (May 2025, state)

Missouri figures are published directly by the U.S. Bureau of Labor Statistics for Missouri (May 2025). They are not estimated or adjusted.

Source year 2025. Last reviewed July 17, 2026. Full methodology

Estimated figures for Missouri. Last reviewed July 17, 2026.